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There are several matches for 'translation initiation inhibitor'.
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2607 matches
showing page 1 of 131
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organism
protein
1)
Homo sapiens
EIF2AK4 - eIF-2-alpha kinase GCN2; Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic
translation
initiation
factor 2 (eIF-2- alpha/EIF2S1) on 'Ser-52' in response to low amino acid availability. Plays a role as an activator of the integrated stress response (ISR) required for adapatation to amino acid starvation. Converts phosphorylated eIF-2-alpha/EIF2S1 either to a competitive
inhibitor
of the
translation
initiation
factor eIF-2B, leading to a global protein synthesis repression, and thus to a reduced overall utilization of amino acids, or to a transla [...]
[a.k.a. ENST00000559032.1, URS00008B9903, ENST00000316599]
2)
Homo sapiens
EIF2AK3 - Eukaryotic
translation
initiation
factor 2-alpha kinase 3; Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic
translation
initiation
factor 2 (eIF-2- alpha/EIF2S1) on 'Ser-52' during the unfolded protein response (UPR) and in response to low amino acid availability. Converts phosphorylated eIF-2-alpha/EIF2S1 either in a global protein synthesis
inhibitor
, leading to a reduced overall utilization of amino acids, or to a
translation
initiation
activator of specific mRNAs, such as the transcriptional activator ATF4, and hence allowing ATF4-mediated [...]
[a.k.a. UPI0010893AAF, XM_017005376, ENST00000652736]
3)
Homo sapiens
EIF4E3 - Eukaryotic
translation
initiation
factor 4E type 3; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the
initiation
of protein synthesis. May act as an
inhibitor
of EIF4E1 activity (By similarity).
[a.k.a. Q6NUT1, Q8N5X7, CCDS33786]
4)
Mus musculus
Eif2ak4 - eIF-2-alpha kinase GCN2; Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic
translation
initiation
factor 2 (eIF-2- alpha/EIF2S1) on 'Ser-52' in response to low amino acid availability. Plays a role as an activator of the integrated stress response (ISR) required for adapatation to amino acid starvation. Converts phosphorylated eIF-2- alpha/EIF2S1 either to a competitive
inhibitor
of the
translation
initiation
factor eIF-2B, leading to a global protein synthesis repression, and thus to a reduced overall utilization of amino acids, or to a transl [...]
[a.k.a. Eif2ak4-208, UPI0000D778C7, XP_017174398]
5)
Mus musculus
Eif2ak3 - Eukaryotic
translation
initiation
factor 2-alpha kinase 3; Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic
translation
initiation
factor 2 (eIF-2- alpha/EIF2S1) on 'Ser-52' during the unfolded protein response (UPR) and in response to low amino acid availability. Converts phosphorylated eIF-2-alpha/EIF2S1 either in a global protein synthesis
inhibitor
, leading to a reduced overall utilization of amino acids, or to a
translation
initiation
activator of specific mRNAs, such as the transcriptional activator ATF4, and hence allowing ATF4-mediated [...]
[a.k.a. XP_011239504.1, NP_034251, R-MMU-392499]
6)
Mus musculus
Eif4e3 - Eukaryotic
translation
initiation
factor 4E type 3; Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the
initiation
of protein synthesis. May act as an
inhibitor
of EIF4E1 activity.
[a.k.a. NP_080105, ENSMUSG00000093661, eIF4E type 3]
7)
Escherichia coli K12
yoeB - Toxin of the YoeB-YefM toxin-antitoxin system; Toxic component of a type II toxin-antitoxin (TA) system. Its mode of function is controversial; it has been proposed to be an mRNA interferase but also an
inhibitor
of
translation
initiation
. When overproduced in wild-type cells, inhibits bacterial growth and
translation
by cleavage of mRNA molecules while it has a weak effect on colony forming ability. Overproduction of Lon protease specifically activates YoeB-dependent mRNA cleavage, leading to lethality. YefM binds to the promoter region of the yefM-yeoB operon to repress transcription [...]
[a.k.a. b4539, ABD18681.1, P69348]
8)
Saccharomyces cerevisiae
TIF5 -
Translation
initiation
factor eIF5; functions both as a GTPase-activating protein to mediate hydrolysis of ribosome-bound GTP and as a GDP dissociation
inhibitor
to prevent recycling of eIF2; Belongs to the eIF-2-beta/eIF-5 family.
[a.k.a. YPR041W, SUI5, 2FUL]
9)
Acidovorax sp. KKS102
AFU43942.1 - COG0251 Putative
translation
initiation
inhibitor
, yjgF family.
[a.k.a. C380_01080,
Translation initiation inhibitor
, K0HTF0_9BURK,
translation initiation inhibitor
]
10)
Acinetobacter ursingii
CJ183_03505 - Unannotated protein.
[a.k.a. GCA_000934145_01863, unannotated protein, BBF76367,
Translation initiation inhibitor
]
11)
Actinobacillus equuli
ACEE_01275 - Endoribonuclease L-PSP; Derived by automated computational analysis using gene prediction method: Protein Homology.
[a.k.a. AIZ78432.1, AIZ78432,
Translation initiation inhibitor
]
12)
Actinoplanes sp. N902109
L083_7908 -
Translation
initiation
inhibitor
.
[a.k.a. AGL21418.1, WP_015625974.1,
Translation initiation inhibitor
,
translation initiation inhibitor
]
13)
Advenella kashmirensis W13003
ETF01260.1 -
Translation
initiation
inhibitor
; Derived by automated computational analysis using gene prediction method: Protein Homology.
[a.k.a. W822_18555,
Translation initiation inhibitor
, ETF01260,
translation initiation inhibitor
]
14)
Advenella kashmirensis WT001
AFK62246.1 - COG0251 Putative
translation
initiation
inhibitor
, yjgF family.
[a.k.a. TKWG_09695,
Translation initiation inhibitor
, I3UB58,
translation initiation inhibitor
]
15)
Aeromonas media
B224_4990 -
Translation
initiation
inhibitor
.
[a.k.a. AHX62856.1,
Translation initiation inhibitor
, A0A023RMV9_AERME,
translation initiation inhibitor
]
16)
Aeromonas schubertii
ALP40282.1 -
Translation
initiation
inhibitor
.
[a.k.a. WL1483_4478, ALP40282, asr:WL1483_4478,
Translation initiation inhibitor
,
translation initiation inhibitor
, ...]
17)
Afipia sp. Root123D2
KQW22772.1 -
Translation
initiation
inhibitor
; Derived by automated computational analysis using gene prediction method: Protein Homology.
[a.k.a. ASC80_05360,
Translation initiation inhibitor
, NZ_LMDP01000001.1,
translation initiation inhibitor
]
18)
Agarivorans albus
AALB_4221 -
Translation
initiation
inhibitor
.
[a.k.a. GAD04141.1, WP_016403908.1,
Translation initiation inhibitor
,
translation initiation inhibitor
]
19)
Agrobacterium albertimagni
QWE_03803 - COG0251 Putative
translation
initiation
inhibitor
, yjgF family.
[a.k.a. EKF60885.1, NZ_ALJF01000003.1,
Translation initiation inhibitor
,
translation initiation inhibitor
]
20)
Agrobacterium fabrum
Atu3926 -
Translation
initiation
inhibitor
.
[a.k.a. AAK89494.2, 1135800,
Translation initiation inhibitor
,
translation initiation inhibitor
]
2607 matches
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